Anton Lennikov Selected Research

N- (3,5- bis(trifluoromethyl)phenyl)- 5- chloro- 2- hydroxybenzamide

1/2018	Selective IKK2 inhibitor IMD0354 disrupts NF-κB signaling to suppress corneal inflammation and angiogenesis.
9/2014	IκB kinase-β inhibitor IMD-0354 beneficially suppresses retinal vascular permeability in streptozotocin-induced diabetic mice.
1/2012	Amelioration of endotoxin-induced uveitis treated with an IκB kinase β inhibitor in rats.

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Anton Lennikov Research Topics

Disease

14	Inflammation (Inflammations) 10/2023 - 01/2012
5	Macular Degeneration (Age-Related Maculopathy) 01/2022 - 01/2019
5	Pathologic Neovascularization 01/2020 - 01/2016
4	Uveitis 12/2014 - 01/2012
3	Choroidal Neovascularization 01/2021 - 01/2013
3	Blindness (Hysterical Blindness) 10/2020 - 01/2016
2	Hypoxia (Hypoxemia) 12/2021 - 01/2019
2	Retinal Degeneration 08/2020 - 02/2020
2	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2020 - 09/2014
2	Intussusception 01/2019 - 01/2016
2	Corneal Neovascularization 01/2019 - 01/2017
1	Bites and Stings (Sting) 10/2023
1	Tauopathies 01/2023
1	Keratoconus 01/2023
1	Neuroinflammatory Diseases 01/2023
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022
1	Glucosephosphate Dehydrogenase Deficiency 02/2020
1	Disease Progression 11/2019
1	Insulin Resistance 11/2018
1	Cataract (Cataracts) 01/2017
1	Glaucoma 01/2017
1	Neoplasms (Cancer) 01/2016
1	Neoplasm Metastasis (Metastasis) 01/2016
1	Iritis 12/2014
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2014
1	Reperfusion Injury 01/2014

Drug/Important Bio-Agent (IBA)

8	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 01/2013
7	Retinaldehyde (Retinal)IBA 01/2023 - 01/2016
4	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2014
3	LipopolysaccharidesIBA 01/2023 - 01/2014
3	N- (3,5- bis(trifluoromethyl)phenyl)- 5- chloro- 2- hydroxybenzamideIBA 01/2018 - 01/2012
3	EndotoxinsIBA 01/2014 - 01/2012
2	CXC ChemokinesIBA 01/2022 - 08/2020
2	RNA (Ribonucleic Acid)IBA 08/2020 - 02/2020
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020 - 11/2018
2	AntioxidantsIBA 01/2020 - 11/2018
2	Phosphotransferases (Kinase)IBA 01/2018 - 01/2012
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2017 - 01/2017
1	InflammasomesIBA 10/2023
1	DNA (Deoxyribonucleic Acid)IBA 10/2023
1	InterferonsIBA 10/2023
1	Oxygen (Dioxygen)IBA 12/2021
1	Biocompatible Materials (Biomaterials)IBA 10/2020
1	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 04/2020
1	Phosphates (Orthophosphate)IBA 02/2020
1	NADP (NADPH)IBA 02/2020
1	Nicotine FDA Link 02/2020
1	Glutathione (Reduced Glutathione)IBA 02/2020
1	Adenosine (Adenocard)FDA LinkGeneric 02/2020
1	Rhodopsin (Visual Purple)IBA 02/2020
1	Chemokine ReceptorsIBA 01/2019
1	Prostaglandins FIBA 11/2018
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2017
1	SteroidsIBA 01/2017
1	ChemokinesIBA 01/2016
1	PyridoxamineIBA 12/2014
1	Biomarkers (Surrogate Marker)IBA 12/2014
1	Streptozocin (Streptozotocin)FDA Link 09/2014
1	Phospholipases A2 (Phospholipase A2)IBA 01/2014
1	EnzymesIBA 01/2014
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2014
1	IronIBA 01/2014
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2014
1	Therapeutic UsesIBA 01/2014
1	Tissue Kallikreins (Tissue Kallikrein)IBA 01/2013
1	IMD-1041IBA 01/2012
1	ProdrugsIBA 01/2012

Therapy/Procedure

4	Sutures (Suture) 01/2023 - 01/2017
3	Lasers (Laser) 01/2021 - 01/2013
2	Therapeutics 11/2018 - 01/2017
1	Contact Lenses 12/2021
1	Aftercare (After-Treatment) 11/2019
1	Oral Administration 12/2014
1	Subcutaneous Injections 01/2014